Wholesale Natural Papain Bromelain Mix Powder Suppliers, Factories

CAS No.: 9001-73-4 / 9001-00-7

Specification: 100–2400 GDU/g

Appearance: Light yellow to yellow fine powder

Test Method: HPLC / UV-Vis

Solubility: Soluble in water

Applications: Dietary supplements,Skincare products

Package: 1–25kg or customized

Sample: 10–50g Sample For free

Storage: Cool dry place away from direct sunlight

Certificates: ISO22000, Kosher, Halal, Organic(EU), USDA, FSSC22000, FAD, SGS, cGMP

Shelf life: 2 years, Available in bulk, Private Label/OEM&ODM

Product Description

Customized Papain-Bromelain Enzyme Blend | cGMP Certified OEM Supply

Natural Papain Bromelain Blend Powder is a blend of plant enzymes derived from papaya and pineapple that is designed to aid digestion, protein breakdown, and is widely used in functional foods and nutraceuticals. This finely ground enzyme powder, also known as papain bromelain extract or proteolytic enzyme blend, combines the benefits of two powerful proteases into a single, easy-to-use format.

Extracted from the latex of green papaya fruit, papain powder is known for its powerful proteolytic activity, especially in alkaline environments. It is widely used in digestive aids, meat tenderizers, and topical wound care formulations. Bromelain powder, on the other hand, is derived from pineapple stems and works best over a wider pH range. It is widely recognized for its anti-inflammatory, anti-edema, and digestive benefits in food processing and supplement products.

Such enzyme blends are gaining popularity due to their natural origin, versatility, and compatibility with clean label formulations. Our natural papain-bromelain blend powders are standardized for consistent enzyme activity (customizable, e.g. 100-2400 GDU/g) and manufactured in cGMP certified facilities for full traceability and food grade compliance. Unlike generic suppliers, we don't simply blend powders - we carefully co-process and fine-tune the blend ratio to achieve the best synergy between papain and bromelain, ensuring better functional performance in real-world applications. We also offer OEM and ODM services tailored to your product needs - whether you require private labeling, custom packaging, capsule filling or formulation support.

Why choose our natural papain bromelain powder blend

1. Controllable enzyme ratio for improved application efficiency

Our R&D team has analyzed more than 60 formulation variations and performed real-time performance testing in solid and liquid systems. Depending on your application (e.g. tablets, beverages, topical creams), we can adjust the ratio of bromelain to papain to suit pH stability, release profile, and target substrate digestion.

2. Enzyme activity validation

Each batch is standardized for enzyme potency (e.g. 100-2400 GDU/g) using high-performance liquid chromatography (HPLC) and ultraviolet-visible spectrophotometer (UV-Vis) methods to ensure that your formulations receive consistent protease activity, not just the amount of bulk powder.

3. Excellent solubility and particle control

Our premixes have an average fineness of D90 < 200 mesh, which improves dispersibility in instant beverage powders and capsule dosage forms. This reduces the risk of precipitation or agglomeration during industrial-scale filling or consumer use.

4. True OEM/ODM partnership

We don't just sell powders, we offer comprehensive OEM and ODM support:

  • Customized mix ratios and enzyme concentrations
  • Private label services available with multi-lingual regulatory support
  • Packaging solutions covering a wide range of formats from 25 kg drums to sachets, capsules or effervescent tablets
  • Fast delivery: Standard format lead time as short as 7-10 days
  • Low MOQ options, starting from 1 kg for pilot batches

COA

Items Specification Result Test Method
Appearance Light yellow fine powder Complies Visual
Odor & Taste Characteristic Complies Organoleptic
Solubility Soluble in water Complies In-house
Loss on Drying ≤ 5.0% 3.12% USP <731>
Ash ≤ 5.0% 2.84% AOAC 942.05
Particle Size 100% pass 80 mesh Complies AOAC 972.03
Papain Activity ≥ 600 TU/mg (equivalent to 600,000 U/g) 632 TU/mg UV-Vis
Bromelain Activity ≥ 1200 GDU/g 1280 GDU/g USP-NF
Total Enzyme Activity Custom blend ≥ 1200 GDU/g 1315 GDU/g Internal Standard
Total Plate Count ≤ 1,000 CFU/g 320 CFU/g USP <2021>
Yeast & Mold ≤ 100 CFU/g 25 CFU/g USP <2021>
E. coli Negative/10g Negative USP <2022>
Salmonella Negative/25g Negative USP <2022>
Heavy Metals ≤ 10 ppm 4.3 ppm ICP-MS
Arsenic (As) ≤ 2 ppm 0.19 ppm ICP-MS
Lead (Pb) ≤ 3 ppm 0.76 ppm ICP-MS
Cadmium (Cd) ≤ 1 ppm 0.21 ppm ICP-MS
Mercury (Hg) ≤ 0.1 ppm <0.01 ppm ICP-MS
GMO Status Non-GMO Complies Declaration
Irradiation Not irradiated Complies Declaration

What is bromelain and papain used for?

1. Dietary supplements

Function: Aids digestion by breaking down proteins into peptides and amino acids

Dosage form: Capsules, tablets, chewable tablets, enzyme mixtures, enzyme softgels

Use: Used as a standalone digestive enzyme or multi-enzyme complex

2. Food processing

Function: Tenderize meat, hydrolyze protein, clarify beverages

Application: Marinades, meat seasoning powder, protein shakes, functional beverages

Use: Improve the bioavailability and texture of protein in processed foods

3. Cosmetics and skin care

Function: Gentle exfoliation, digestion of protein, removal of dead skin

Application: Facial masks, skin rejuvenation products, enzyme cleansers

Use: Low concentrations (usually <1%) for topical preparations

4. Pharmaceuticals

Function: Anti-inflammatory, debridement for wound healing

Application: Topical enzyme ointment, oral anti-edema formula

Usage: As directed by a doctor; must meet pharmacopoeia standards

5. Animal health

Function: Enhance protein digestion in pet food and animal supplements

Application: Dog and cat digestion powder, livestock nutrition formula

Recommended Dosage

  • Dietary Supplements: 100–500 mg per day (standard 1200 GDU/g activity)
  • Food Processing: 100–300 mg per kg of food material
  • Topical Cosmetics: 0.1%–1% in final product formulation
  • Pet Supplements / Animal Feed: 100–300 mg per kg of feed

Reliable Papain Bromelain Supplier

As a trusted Papain Bromelain Mix Powder manufacturer, we offer bulk quantities and OEM services to meet your production needs. Our product is backed by ISO, Halal, Kosher, and cGMP certifications, ensuring the highest quality standards.

Our Papain Bromelain Mix Powder is a top choice for companies seeking consistent enzyme activity, custom formulations, and fast delivery. We are committed to building long-term partnerships, providing you with tailored solutions and dedicated support for your business growth. Let's work together to create superior products!

Frequently Asked Questions

Can this enzyme powder be used in vegan or vegetarian products?
Yes, of course. Our papain bromelain blend is 100% plant-based, non-GMO, and contains no animal-derived ingredients, making it ideal for vegan/vegetarian product lines.
Is the enzyme activity stable during formulation or processing?
Our enzyme blends are cryogenically dried and stabilized with maltodextrin or other carriers to maintain activity during storage and mild processing (e.g., cryogenic granulation, capsule filling). Avoid exposure to heat above 60°C or acid during formulation.
Can I customize the ratio of papain to bromelain?
Yes. We offer custom enzyme ratios (e.g., 1:1, 2:1, 1:3) based on your formulation needs, perfect for brands developing specialized digestive blends or food-grade protease systems. We offer OEM/ODM services with low minimum order quantities.
What are the recommended storage conditions for this enzyme blend?
It should be stored in a cool, dry place, ideally at temperatures below 20°C (68°F), in a tightly sealed container. Keep away from direct sunlight, moisture, and strong odors to preserve maximum enzyme potency.
What is the standard shelf life of the powder?
When stored under the recommended conditions in its original unopened packaging, the standard shelf life of our Papain-Bromelain enzyme blend is 24 months.
What quality documentation do you provide for each batch?
We provide a comprehensive Certificate of Analysis (COA) for every batch, detailing active enzyme assay values, heavy metal limits, and microbiological test results. MSDS and allergen declarations are also available upon request.

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