Engineered for high bioavailability, exceptional batch consistency, and rigorous regulatory compliance in the Cibao Valley economic zone.
As the economic engine of the Cibao region and the second-largest metropolitan center in the Dominican Republic, Santiago de los Caballeros has established itself as a premier nexus for pharmaceutical manufacturing, cosmeceutical formulation, and high-value free trade zone (Zona Franca Industrial Victor Espaillat Mera) operations.
Local industrial enterprises are rapidly expanding beyond traditional processing into sophisticated dietary supplement manufacturing, functional beverage blending, and clinical-grade topical skin care. This transformation demands a reliable, highly technical supply partner capable of providing standardized botanical extracts with complete batch traceability, low heavy-metal profile guarantees, and strict conformity with international pharmacopeia standards.
By leveraging direct bulk shipments, customized assay specifications, and full technical documentation support, we bridge the gap between world-class bio-extraction technology and the dynamic manufacturing sector in Santiago de los Caballeros.
Our bioengineering capabilities leverage molecular separation, supercritical fluids, and advanced analytical chemistry to guarantee consistent potency in every batch delivered to Santiago.
Utilizing eco-friendly, solvent-free Supercritical Fluid Extraction (SFE) and dynamic continuous counter-current technology to preserve thermo-sensitive active compounds like Gingerols, Magnolol, and Nobiletin without leaving toxic chemical residues.
Multi-stage ceramic ultrafiltration and nanofiltration combined with macroporous resin chromatographic separation to isolate high-purity phytochemical fractions such as 98% Corosolic Acid, Ecdysterone, and Berberine HCl with laser-focused chemical precision.
Every single production batch undergoes rigorous finger-print assay validation via High-Performance Liquid Chromatography (HPLC), Gas Chromatography-Mass Spectrometry (GC-MS), and Heavy Metal Inductively Coupled Plasma Mass Spectrometry (ICP-MS).
Combining decades of industrial expertise with automated manufacturing intelligence to guarantee supply continuity for Dominican enterprisewide buyers.
Benefiting from the solid foundation provided by its parent company, Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc. focuses on researching, developing, producing, and selling healthy natural ingredients. With more than two decades of industry experience, it has become a global benchmark in phytopharmaceutical manufacturing.
Our operations are supported by three integrated companies — Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc., and Shaanxi Tianben Kangyuan Biotechnology Co., Ltd. — which together operate 3 production bases covering more than 100 acres and process more than 3,000 tons of plant raw materials each year. Our product portfolio includes more than 200 standardized botanical extracts alongside certified organic ingredients.
Our first flagship factory was established in 2012 in Sanyuan City, Xi'an, four years after our company's founding. Through continuous capital investment, technician training, and strict cGMP quality management systems, Sanyuan Factory has evolved into a state-of-the-art processing facility.
100,000-Class Clean Room Operations: All final processing steps—including powder collection, micro-crushing, sieving, precision blending, and vacuum packaging—are performed in an ultra-pure Class 100,000 cleanroom environment. Facility operators strictly adhere to aseptic protocols, wearing sterile gowns, masks, and gloves to guarantee zero microbial cross-contamination.




Providing custom botanical formulations, precise particle size customization, and enhanced solubility matrices to empower local finished-good brands.
High-density, instantized powders ideal for hard-shell capsules, compressed tablets, and stick-pack powders. Featuring active biomarkers like Corosolic Acid for metabolic support and Sulforaphane / Glucoraphanin for cellular detoxification.
Ultra-pure bio-actives including Nobiletin, Magnolol, and Gingerol designed for anti-aging serums, skin-brightening creams, and anti-inflammatory dermatological formulations with complete transdermal compatibility.
Water-soluble, low-bitterness extracts such as Ceylon Cinnamon Bark Extract and Piperine for ready-to-drink functional beverages, botanical wellness teas, and meal replacement formulations targeted at health-conscious consumers.
Eliminating market-entry friction for Santiago clients through rigorous global quality certifications and streamlined logistics.
Navigating food and pharmaceutical registration in the Dominican Republic requires comprehensive analytical documentation. We supply full technical dossiers for every batch, including Certificate of Analysis (CoA), Heavy Metal ICP-MS reports, Pesticide Residue testing (EU & US FDA limits), Ethylene Oxide (ETO) free statements, and non-GMO affidavits to guarantee seamless clearance through DIGEMAPS regulatory reviews.
With direct sea freight options connecting major international ports to Puerto Plata Port and Rio Haina / Caucedo, alongside air express capabilities straight into Cibao International Airport (STI) in Santiago de los Caballeros, we offer flexible shipping terms (FOB, CIF, DDP) to maintain unbroken stock availability for local production plants.
Browse our core catalog of lab-tested active phytochemicals engineered for pharmaceutical, cosmetic, and nutritional applications.
Risk mitigation, standardized contract specifications, and direct manufacturing partnerships for procurement directors in Santiago de los Caballeros.
We work directly with your R&D and QA teams in Santiago to establish precise target assay percentages, active compound ratios, bulk density specifications, moisture control thresholds, and mesh sizes tailored to your encapsulation or tableting machinery.
Prior to dispatching commercial scale shipments, we provide lab-certified Pre-Shipment Samples accompanied by full HPLC spectra, 3rd party laboratory verification reports (SGS/Eurofins available), and safety data sheets (MSDS).
Ingredients are vacuum-sealed in food-grade double aluminum foil bags inside heavy-duty fiber drums. Shipments are consolidated with climate control measures to prevent heat degradation during transatlantic and Caribbean maritime transport.
Our dedicated regulatory specialists assist Santiago clients with technical filings for DIGEMAPS compliance, dosage validation, stability testing documentation, and active synergy blending recommendations.
Insights into our plant extract manufacturing, shipping protocols to Santiago, quality controls, and custom OEM/ODM services.
Partner with a proven global bio-extraction leader. Request factory-direct pricing, custom assay specifications, and complimentary evaluation samples today.