High-purity phytochemical isolates optimized for skin barrier integration, cellular rejuvenation, and transdermal stability.
Israel sits at the global crossroads of high-tech biotechnology innovation and natural dermo-cosmetics. Home to the legendary therapeutic minerals of the Dead Sea and world-leading research universities in Rehovot, Haifa, and Jerusalem, the Israeli market demands ingredients of unmatched efficacy, absolute stability, and robust scientific substantiation.
In recent years, the shift towards Longevity Science and Cellular Anti-Aging has revolutionized the Tel Aviv skincare and dietary supplement startups. Brands no longer look for simple topical moisturizers; they require active ingredients that offer high Information Gain—scientific efficacy demonstrated via cellular assays, clinical evaluations, and clean extraction profiles.
Whether formulating high-protection SPF creams designed for the intense Mediterranean sun or designing complex senolytic dietary formulations, our raw ingredients undergo strict pharmaceutical-grade extraction to ensure they deliver targeted, measurable results to consumers in Israel.
Developing photostable antioxidants like Trans-Pterostilbene to mitigate heavy UV radiation exposure characteristic of the Levant region.
Providing strict trace-chemical auditing, non-GMO certificates, and Kosher-compliant processing pipelines for ingestion-grade collagens and bioactive molecules.
Optimizing plant extract profiles (like Pomegranate & Black Rice) to work dynamically alongside high-concentration mineral formulations.
Utilizing micro-milling and lipid-soluble carrier systems to enhance transdermal penetration of sensitive whitening agents like Kojic Acid Dipalmitate.
A Global Leader in Natural Bioactive Ingredients
Benefiting from the solid foundation provided by its parent company, Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc. focuses on researching, developing, producing, and selling healthy natural ingredients. With more than two decades of industry experience, we have become a global pioneer specializing in providing high-quality plant extracts and customized solutions to global customers. Our services meet the precise regulatory and clinical demands of industries including herbal medicine, health foods, dietary supplements, food and beverages, daily chemicals, and cosmetics.
Our operations are supported by three companies—Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc., and Shaanxi Tianben Kangyuan Biotechnology Co., Ltd.—which together operate 3 state-of-the-art production bases covering more than 100 acres and process more than 3,000 tons of raw materials annually. Our dynamic product range includes more than 200 plant extracts, alongside certified organic ingredients, catering to the global demand for environmentally friendly, sustainable, and highly effective biological solutions. Exporting to 60% of the world's countries, we proudly serve clients across 200+ countries and regions.
Our primary extraction facility, the Sanyuan Factory, was established in 2012 in Sanyuan City, Xi'an. From our early years of development, we have continually upgraded our infrastructure, importing cutting-edge supercritical CO2 extraction systems, high-pressure column chromatography, and clean spray-drying towers.
All critical stages—including raw powder collection, crushing, sieving, micro-mixing, and vacuum drying—are meticulously performed within a Class 100,000 Cleanroom. Our technical operators strictly adhere to aseptic protocols, wearing sterile gowns, anti-static masks, and dual-layer gloves. By maintaining absolute environmental purity and rigorous quality control, we ensure our active ingredients surpass the microbial and purity benchmarks set by European and Israeli health authorities.
Bridging international logistical gaps and providing documentation tailored for the Ministry of Health (MOH) of Israel.
We work with tier-one shipping lines to route cargo directly to Ashdod and Haifa ports, handling custom clearances with promptness to avoid manufacturing bottlenecks.
Many of our dietary ingredients, including hydrolyzed bovine collagen and α-Ketoglutarate, are auditable for Kosher certifications to meet domestic market regulations.
We supply complete documentation packets: Certificate of Analysis (COA) measured by HPLC/UV, heavy metal analysis, pesticide residue tests, and GMO declarations.
Discover our comprehensive range of high-efficacy anti-aging, cellular longevity, and skin-whitening active raw materials.
Accelerating product development from molecular isolation to ready-to-fill formulations.
HPLC-verified standardization of active compounds (such as Ellagic Acid from Pomegranate or Trans-Pterostilbene) to secure exact batch-to-batch consistency for pharmaceutical-grade applications.
Resolving absorption challenges through micro-emulsification and oil-soluble modifications (e.g., Kojic Acid Dipalmitate), ensuring excellent stability inside lipid phases and cosmetic emulsions.
Collaborating with local R&D laboratories in Israel to develop unique combinations of cellular longevity promoters (AKG, GABA, Neuric Acid) and botanical complexes.
Addressing technical, logistical, and compliance questions regarding importing active ingredients to Israel.
Q: What documentation do you provide for cosmetics registration in Israel?
A: We provide complete regulatory documentation to satisfy Ministry of Health (MOH) requirements, including detailed COA (HPLC verified), allergen declarations, heavy metal testing limits, BSE/TSE statements, and manufacturing flowcharts.
Q: How do you handle shipping temperature-sensitive active ingredients to Ashdod or Haifa ports?
A: We use climate-controlled logistics pathways and protective vacuum-sealed packaging. For heat-sensitive peptides, enzymes, and natural extracts, we can coordinate refrigerated containers (reefers) to ensure bio-activity is preserved throughout transit.
Q: Are your nutraceutical powders (e.g., AKG, GABA, Collagen) Kosher-certified?
A: Yes, many of our key botanical extracts and biochemical powders are manufactured in facilities that comply with Kosher standards. Please indicate your specific Kosher requirements (e.g., Badatz or general Rabbinate recognition) when submitting your inquiry, and we will provide the corresponding batch-level certificates.
Q: What is the typical Minimum Order Quantity (MOQ) for custom ODM formulations?
A: For standard ingredients in stock, our MOQ starts at 1kg to 25kg (standard drum size). For customized ODM extractions or specific particle size adjustments, our MOQ depends on the raw material's yield but typically starts at 100kg.
Connect directly with our technical sales managers and regulatory experts to obtain samples, request detailed spec sheets, or schedule a video consultation.
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