Dihydroberberine HCl (DHB), also known as reduced berberine or DHB HCl, is an advanced derivative of traditional berberine. Through hydrogenation, DHB achieves higher bioavailability (5x higher than standard berberine) while retaining the core benefits of its parent compound - blood sugar regulation, metabolic support, and cardiovascular protection. DHB's optimized molecular structure ensures rapid absorption and prolonged in vivo activity.
The nutraceutical market is currently focused on high-purity DHB powder as a premium, differentiated product. Our DHB HCl is standardized to ≥97% purity, surpassing generic berberine products often diluted with fillers. We isolate DHB for targeted efficacy, especially in AMPK activation, utilizing cGMP certified and FDA registered facilities to ensure batch-to-batch consistency and compliance with NSF/USP/EP standards.
Proprietary extraction and purification ensures 99.5%+ purity, leading to higher bioavailability and efficacy for end-user formulations.
Advanced stabilization technology maintains 95% potency for more than 24 months, reducing waste and reorder costs.
We offer custom dosage granules (50-500 mg) and small batch scalability starting from 50 kg pilot batches.
15+ patented processes (solvent-free crystallization) reduce heavy metal residues to <0.1 ppm with 100% batch testing.
| Test Item | Specification | Test Method | Result |
|---|---|---|---|
| Appearance | Yellow powder | Visual Inspection | Yellow powder |
| Purity (HPLC) | ≥98% | HPLC | 99.3% |
| Loss on Drying | ≤5% | Drying at 105°C | 3.2% |
| Heavy Metals | ≤10ppm | ICP-MS | <5ppm |
| Arsenic (As) | ≤1ppm | ICP-MS | <0.5ppm |
| Lead (Pb) | ≤1ppm | ICP-MS | <0.5ppm |
| Cadmium (Cd) | ≤1ppm | ICP-MS | <0.2ppm |
| Mercury (Hg) | ≤0.1ppm | ICP-MS | <0.05ppm |
| Total Plate Count | ≤1000cfu/g | Plate Count Method | 500cfu/g |
| Yeast & Mold | ≤100cfu/g | Plate Count Method | 20cfu/g |
| Microbial Contamination | Negative | PCR Testing | Negative |
| Solubility | Soluble in water/ethanol | Solubility Test | Soluble |
| pH (1% Solution) | 4.5–6.5 | pH Meter | 5.2 |
| Bulk Density | 0.30-0.60g/ml | Bulk Density Method | 0.45g/ml |
| Particle Size | 100% pass 80 mesh | Sieve Analysis | 100% pass 80 mesh |
Commonly used to maintain healthy blood sugar levels and enhance insulin sensitivity.
Powerful antioxidant properties help reduce oxidative stress, boost collagen synthesis, and enhance skin elasticity.
Anti-inflammatory benefits help soothe irritated skin and promote a clear complexion for acne-prone skin.
Supports fat metabolism, beneficial for overall metabolic health and body fat reduction.
Note: Suggested dose may vary based on individual health conditions and final product formulation. Always consult a healthcare professional before use.
We specialize in the production of high-purity DHB powders that meet cGMP, ISO and FDA standards. Whether you need bulk powders, custom blends or private label solutions, we deliver with fast delivery and strict quality control. Partner with us to enhance your formulations.