High-Quality Pure Dihydroberberine HCl (DHB) Powder Factories, Factory

CAS No.: 483-15-8

Specification: 98%

Appearance: Yellow powder

Test Method: HPLC

Solubility: Soluble in water and ethanol

Applications: Anti-inflammatory properties

Package: 1–25kg or customized

Sample: 10-50g Sample For free

Storage: Cool dry place away from direct sunlight

Certificates: ISO22000, Kosher, Halal, Organic(EU), USDA, FSSC22000, FAD, SGS, cGMP

Shelf life: 2 years, Available in bulk, Private Label/OEM&ODM

Product Description

Dihydroberberine HCl (DHB) Powder: Next-Generation Berberine

Dihydroberberine HCl (DHB), also known as reduced berberine or DHB HCl, is an advanced derivative of traditional berberine. Through hydrogenation, DHB achieves higher bioavailability (5x higher than standard berberine) while retaining the core benefits of its parent compound - blood sugar regulation, metabolic support, and cardiovascular protection. DHB's optimized molecular structure ensures rapid absorption and prolonged in vivo activity.

The nutraceutical market is currently focused on high-purity DHB powder as a premium, differentiated product. Our DHB HCl is standardized to ≥97% purity, surpassing generic berberine products often diluted with fillers. We isolate DHB for targeted efficacy, especially in AMPK activation, utilizing cGMP certified and FDA registered facilities to ensure batch-to-batch consistency and compliance with NSF/USP/EP standards.

Why Choose Our Dihydroberberine HCl (DHB) Powder?
🔬
High Purity and Stability

Proprietary extraction and purification ensures 99.5%+ purity, leading to higher bioavailability and efficacy for end-user formulations.

Longer Shelf Life

Advanced stabilization technology maintains 95% potency for more than 24 months, reducing waste and reorder costs.

Custom OEM Solutions

We offer custom dosage granules (50-500 mg) and small batch scalability starting from 50 kg pilot batches.

📊
20 Years of R&D Experience

15+ patented processes (solvent-free crystallization) reduce heavy metal residues to <0.1 ppm with 100% batch testing.

📋 Certificate of Analysis (COA)
Test Item Specification Test Method Result
AppearanceYellow powderVisual InspectionYellow powder
Purity (HPLC)≥98%HPLC99.3%
Loss on Drying≤5%Drying at 105°C3.2%
Heavy Metals≤10ppmICP-MS<5ppm
Arsenic (As)≤1ppmICP-MS<0.5ppm
Lead (Pb)≤1ppmICP-MS<0.5ppm
Cadmium (Cd)≤1ppmICP-MS<0.2ppm
Mercury (Hg)≤0.1ppmICP-MS<0.05ppm
Total Plate Count≤1000cfu/gPlate Count Method500cfu/g
Yeast & Mold≤100cfu/gPlate Count Method20cfu/g
Microbial ContaminationNegativePCR TestingNegative
SolubilitySoluble in water/ethanolSolubility TestSoluble
pH (1% Solution)4.5–6.5pH Meter5.2
Bulk Density0.30-0.60g/mlBulk Density Method0.45g/ml
Particle Size100% pass 80 meshSieve Analysis100% pass 80 mesh
💡 Primary Applications of Dihydroberberine
1. Blood Sugar Support

Commonly used to maintain healthy blood sugar levels and enhance insulin sensitivity.

2. Anti-Aging

Powerful antioxidant properties help reduce oxidative stress, boost collagen synthesis, and enhance skin elasticity.

3. Skin Health

Anti-inflammatory benefits help soothe irritated skin and promote a clear complexion for acne-prone skin.

4. Weight Management

Supports fat metabolism, beneficial for overall metabolic health and body fat reduction.

📌 Recommended Dosage
  • Supplement Use: 100-200 mg daily (may be taken in divided doses).
  • Skin Care Use: 0.5-1% in formulations (serums, creams or masks).
  • Metabolic Health Use: 200-400 mg daily, or as directed by a healthcare professional.

Note: Suggested dose may vary based on individual health conditions and final product formulation. Always consult a healthcare professional before use.

🚚 Trusted Dihydroberberine (DHB) Supplier

We specialize in the production of high-purity DHB powders that meet cGMP, ISO and FDA standards. Whether you need bulk powders, custom blends or private label solutions, we deliver with fast delivery and strict quality control. Partner with us to enhance your formulations.

Frequently Asked Questions
Does dihydroberberine help slow down aging?
Yes, dihydroberberine is a powerful antioxidant that can reduce oxidative stress, a key factor in skin aging. It helps maintain skin health by promoting collagen production and improving skin elasticity.
How does dihydroberberine improve metabolism?
Dihydroberberine supports healthy metabolism by enhancing mitochondrial function and insulin sensitivity. It also helps with fat burning, making it ideal as a weight management supplement.
What is the best way to take dihydroberberine for weight loss?
For weight loss, it is usually taken in supplement form (100-200 mg daily). It supports fat metabolism and insulin regulation, helping to maintain healthy blood sugar levels.
Is DHB better than regular Berberine HCl?
Yes, DHB has significantly higher bioavailability (approximately 5 times higher) than standard berberine. This means lower doses are required to achieve the same or better therapeutic effects with fewer gastrointestinal side effects.
Can DHB be used in topical cosmetic formulations?
Absolutely. At concentrations of 0.5-1%, it serves as an excellent anti-aging and skin-brightening ingredient due to its anti-inflammatory and antioxidant properties.
What is the purity level of your DHB powder?
Our DHB powder is standardized to ≥98% purity, with proprietary processes often reaching 99.5%+, ensuring maximum efficacy and minimal contaminants.

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