Global Standard Ingredients for Modern Health Applications
Bifidobacterium longum is a multifunctional probiotic strain naturally inhabiting the human gastrointestinal tract. As a premier Bifidobacterium longum manufacturer, we focus on its unique ability to stabilize the gut microbiota, modulate immune responses, and produce short-chain fatty acids (SCFAs). Our research highlights its critical role in competitive exclusion of pathogens and enhancing the intestinal barrier function.
Unlike standard probiotics, our B. longum undergoes a proprietary Triple-Layer Microencapsulation process. This ensures that over 90% of the live bacteria survive the harsh acidic environment of the stomach, reaching the colon where they provide maximum therapeutic impact. This technical edge provides significant information gain for formulators seeking high-efficacy products.
The global market for B. longum is expanding beyond dietary supplements into functional beverages, infant formulas, and even cosmeceuticals. As leading Bifidobacterium longum suppliers, we support the 2024 trend of "Psychobiotics," where B. longum is utilized for its brain-gut axis benefits, reducing anxiety and improving cognitive focus in clinical applications.
Rooted in Tradition, Driven by Biotechnology
Benefiting from the solid foundation provided by its parent company, Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc. focuses on researching, developing, producing and selling healthy natural ingredients. With more than two decades of industry experience, it has become a leader in the field, specializing in providing high-quality plant extracts and customized solutions to global customers.
Our operations are supported by three companies - Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc. and Shaanxi Tianben Kangyuan Biotechnology Co., Ltd. - which together operate 3 production bases covering more than 100 acres and process more than 3,000 tons of plant raw materials each year. Exporting to 60% of the world's countries, serving more than 500 customers from all walks of life.
The Evolution of Probiotic Engineering
Utilizing automated 50-ton fermenters with real-time metabolic monitoring to achieve CFU counts exceeding 500 Billion/g.
Developing AI-driven strain selection for targeted health outcomes, such as B. longum specifically optimized for metabolic syndrome.
Merging B. longum with designer prebiotics (HMOs) to create next-generation "Living Medicines" with localized delivery mechanisms.
Established in 2012, our Sanyuan facility represents our commitment to continuous improvement. We have invested heavily in technology, training, and quality control to strengthen our capabilities. These early efforts laid a strong foundation for our future growth, shaping the high standards of excellence that we uphold today.
Powder collection, crushing and sieving, mixing and drying processes are all performed in a Class 100,000 cleanroom environment. Our operators strictly follow hygiene protocols and wear sterile gowns, masks and gloves to maintain product purity and safety.
Why China remains the global hub for Probiotic manufacturing
From the sourcing of nitrogen-rich fermentation media to the final freeze-drying process, our China-based supply chain is fully integrated, reducing lead times by 30% compared to international competitors.
Processing over 3,000 tons of raw material annually allows us to offer competitive wholesale Bifidobacterium longum pricing without compromising the strain's genetic stability or activity levels.
Our facilities are certified under ISO, HALAL, KOSHER, and follow strict FDA-GRAS guidelines, ensuring that our B. longum is ready for immediate entry into the North American and European markets.
Bridging the Gap between Raw Materials and Consumer Needs
B. longum is increasingly used in yogurt and kombucha to support digestive wellness. Our heat-stable strains are ideal for cold-chain distribution models.
Crucial for the development of early-life immunity. We provide ultra-pure B. longum infantis-compatible strains for premium formula brands.
Applied in skin-microbiome balancing creams. Our B. longum lysates help soothe sensitive skin and strengthen the epidermal barrier.
Expert Answers for Professional Sourcing
Under recommended storage conditions (-20°C to 4°C), our B. longum powder maintains its labeled CFU count for 24 months. For room-temperature applications, we provide specialized microencapsulated versions with an 18-month stability guarantee.
Yes. We offer standard concentrations from 10 Billion CFU/g up to 500 Billion CFU/g. Custom blends with other strains like L. acidophilus or B. lactis are also available via our ODM service.
We provide full documentation including COA, MSDS, Technical Data Sheets (TDS), and stability test reports to assist our partners in their local FDA or EFSA registration processes.
Every batch undergoes DNA sequencing (16S rRNA) to verify the strain identity. This ensures that the B. longum provided is consistent with clinical study benchmarks for efficacy.
Advanced Solutions for the Health and Beauty Industry
Botanical
