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Keratolytic agents are a cornerstone of modern dermatology, designed to break down the protein structure of keratin in the skin. As a leading ODM keratolytic ingredient supplier, we recognize the shift from aggressive chemical peeling to "intelligent exfoliation." Modern formulations require high-purity Alpha Hydroxy Acids (AHAs), Beta Hydroxy Acids (BHAs), and enzymatic keratolytics like papain or Keratoline™ that offer efficacy without compromising the skin barrier.
The global market for keratolytic ingredients is currently witnessing a CAGR of 6.4%, driven by the rising prevalence of hyperkeratotic conditions and the "skinification" of body care. From acne treatments and psoriasis management to anti-aging serums, the demand for stable, high-bioavailability keratolytic actives has never been higher. Our role as a primary supplier is to bridge the gap between lab-scale innovation and industrial-scale reliability.
Utilizing enzymatic catalysis to produce high-purity keratolytics with minimal residual solvents.
Focusing on "Information Gain" in formulation stability for global supply chains.
Full adherence to EU REACH, FDA standards, and China's NMPA regulations.
Benefiting from the solid foundation provided by its parent company, Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc. focuses on researching, developing, producing and selling healthy natural ingredients. With more than two decades of industry experience, it has become a leader in the field, specializing in providing high-quality plant extracts and customized solutions to global customers.
Our operations are supported by three companies - Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc. and Shaanxi Tianben Kangyuan Biotechnology Co., Ltd. - which together operate 3 production bases covering more than 100 acres and process more than 3,000 tons of plant raw materials each year. Exporting to 60% of the world's countries, serving more than 200 countries and regions and more than 500 customers from all walks of life.
The China factory advantage lies not just in scale, but in vertical integration. At our Sanyuan Factory, established in 2012, we have transitioned from traditional extraction to automated, AI-monitored synthesis. This ensures that every batch of keratolytic powder meets the rigorous demands of global pharmaceutical and cosmetic brands.
Our production experience has evolved through continuous investment in technology and quality control. We operate a 100,000-CLASS CLEAN ROOM where powder collection, crushing, sieving, mixing, and drying are performed. This environment eliminates cross-contamination risk—a critical factor for keratolytic ingredients which are often used in sensitive skin applications.
With processing capabilities exceeding 3,000 tons of raw materials annually, we provide the stability of supply that global procurement officers require. Our 200+ plant extract range provides a synergistic "Information Gain" for clients looking to combine keratolytics with soothing agents like Centella Asiatica or Licorice Root.
Global procurement teams are moving away from single-ingredient sourcing toward holistic ODM solutions. The current trend emphasizes "Skin Barrier Respect"—formulating keratolytics that provide the "glass skin" effect without causing inflammatory responses. As a result, there is a surging demand for encapsulated Salicylic Acid and multi-functional exfoliating blends.
Regional insights: In North America, the focus is on "Clinical-Grade" at-home treatments. In the Asia-Pacific region, the demand is driven by mildness and botanical-origin keratolytics. Our ODM services cater to these localized needs by adjusting molecular weights and delivery systems for maximum regional efficacy.
Our 20+ years of experience combined with a 100,000-class cleanroom facility and parent company support from Xi'an Tianben ensures we meet both volume and purity requirements. We don't just supply; we provide technical consultation for ingredient synergy.
Yes. Our ODM services allow us to tailor ingredients—adjusting concentrations, pH stability, and adding soothing plant extracts (like Ginkgo or Polygonum) to reduce potential irritation from exfoliating actives.
Every batch undergoes rigorous HPLC/GC testing. Our facilities are certified organic for specific lines, and we provide comprehensive COA, MSDS, and technical data sheets for all international shipments.
Typically, for stocked items, we ship within 3-5 business days. For customized ODM keratolytic solutions, the lead time ranges from 2-4 weeks depending on the complexity of the formulation and testing required.
We serve over 500 customers from all walks of life, including emerging brands and established global leaders. We offer flexible MOQ to support R&D phases and market testing.
Botanical
