High-Quality Sophora Flavescens Extract | Oxymatrine Powder Manufacturer, Factory

CAS No.: 16837-52-8

Specification: Oxymatrine 98%

Appearance: White to off-white powder

Test Method: HPLC

Solubility: Soluble in water and ethanol

Applications: Skincare, Anti-inflammatory Formulas

Package: 1–25kg or customized

Sample: 10–50g Sample For free

Storage: Cool dry place away from direct sunlight

Certificates: ISO22000, Kosher, Halal, Organic(EU), USDA, FSSC22000, FAD, SGS, cGMP

Shelf life: 2 years, Available in bulk, Private Label/OEM&ODM

Product Description

Oxymatrine Powder: A Potent Botanical Anti-Aging Solution

Sophora flavescens extract is a bioactive ingredient extracted from the root of the plant. Its main alkaloids—matrine (C₁₅H₂₄N₂O) and oxymatrine (C₁₅H₂₄N₂O₂)—have been shown to possess potent anti-aging benefits, including promoting cell regeneration, protecting collagen, and reducing oxidative stress. Studies have shown that oxymatrine inhibits MMP-1 (collagenase) activity, thereby delaying skin aging; while matrine exhibits anti-aging properties by eliminating senescent cells associated with age-related senescence.

The global anti-aging market is projected to exceed $100 billion by 2030, and natural active ingredients like oxymatrine powder are gaining increasing attention in cosmeceuticals, nutricosmetics, and longevity supplements. Unlike synthetic alternatives such as tretinoin, Sophora flavescens extract is mildly irritating and offers multi-pathway anti-aging benefits, making it an ideal choice for serums, oral beauty supplements, and regenerative skincare products.

Why Choose Our Sophora Flavescens Extract?
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High Purity & Bioactivity

HPLC-verified oxymatrine content exceeds 98%. Our low-temperature ethanol extraction technology ensures 15-20% higher alkaloid retention compared to traditional methods. Heavy metal residues are strictly controlled below 0.5 ppm.

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OEM & Customization

Available in ratios from 10:1 to 50:1 concentrates. We offer liposomal formulations for up to 90% absorption and support synergistic blends with hyaluronic acid, NAD+ boosters, or peptides.

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Sustainable Sourcing

Harvested from pollution-free areas, traceable via blockchain. Our products are Non-GMO, allergen-free, and ideal for clean-label brands, meeting strict EU/US safety limits.

Technical Specification (COA)
ITEM SPECIFICATION RESULT TEST METHOD
AppearanceWhite to off-white powderWhite powderVisual
Assay (Oxymatrine)≥ 98.0%98.37%HPLC
Moisture Content≤ 5.0%2.11%USP <921>
Ash Content≤ 5.0%2.76%USP <561>
Sieve Analysis95% pass 80 meshCompliesUSP <786>
Bulk Density0.45–0.65 g/mL0.51 g/mLUSP <616>
Heavy Metals≤ 10 ppm< 5 ppmICP-MS
Lead (Pb)≤ 2 ppm0.31 ppmICP-MS
Total Plate Count≤ 1,000 CFU/g< 100 CFU/gUSP <2021>
GMO StatusNon-GMOCompliesStatement
Primary Applications
COSMETICS
Skincare Solutions

Used in anti-aging creams to inhibit MMPs, anti-acne formulas for its antibacterial properties, and brightening masks to regulate melanin.

SUPPLEMENTS
Nutritional Health

Oral supplements for immune regulation, cellular longevity, and liver health support, contributing to "beauty from within."

PERSONAL CARE
Body & Hair Care

Natural antibacterial agent for body cleansers and scalp care products to reduce inflammation and maintain follicle health.

Recommended Dosage
Creams and Serums: Use 0.1%–0.5% for anti-aging and skin repair.
Masks and Toners: Use 0.2%–1% for brightening and calming.
Hair Care: Use 0.1%–0.3% to promote a healthy scalp environment.
Oral Supplements: 100–300 mg daily, depending on formulation goals.

*Compatibility and stability testing should be conducted prior to final formulation.

Frequently Asked Questions
Can oxymatrine be used long-term in skincare?
Yes. At recommended doses (≤ 1%), it is generally considered safe and non-irritating for long-term use. Patch testing is always recommended for sensitive skin.
Is this ingredient natural or synthetic?
It is a 100% natural alkaloid compound extracted from the root of the traditional medicinal herb Sophora flavescens.
Can I use it in certified organic cosmetics?
Yes. Our powder meets clean beauty standards and is suitable for use in natural and organic skincare lines, being plant-based and non-GMO.
What is the solubility of your Oxymatrine Powder?
Our high-purity powder is soluble in both water and ethanol, making it versatile for various liquid and cream formulations.
Do you offer different concentration ratios?
Yes, we provide customizable ratios from standardized 10:1 extracts to high-potency 50:1 concentrates to meet specific application needs.
How is the stability of the alkaloids maintained?
We utilize low-temperature extraction technology which effectively preserves heat-sensitive alkaloids, ensuring batch-to-batch consistency.

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