Wholesale Polynucleotide (PN) Powder Supplier, Factory

Specification: 99% Purity (Customized available)

Appearance: White to off-white powder

Test Method: HPLC

Solubility: Soluble in water

Applications: Skincare,Wound Healing,Anti-aging Serums

Package: 1–25kg or customized

Sample: 10–50g sample for free

Storage: Cool, dry place away from direct sunlight

Certificates: ISO22000, Kosher, Halal, Organic(EU), USDA, FSSC22000, FDA, SGS, cGMP

Shelf life: 2 years, available in bulk, Private Label/OEM&ODM

Product Description

At the forefront of advanced skincare, Polynucleotide (PN) Powder, also known as DNA Sodium or DNA Cellular Repair Complex, is gaining recognition for its remarkable ability to rejuvenate and restore skin health. This powerful ingredient works by delivering fragments of DNA to the skin, which act as biological signals to stimulate your skin's own repair mechanisms. The result is a visible improvement in skin density, elasticity, and hydration, effectively reducing the appearance of fine lines and wrinkles for a more youthful and resilient complexion.

In the current market, PN-based products are creating a new niche in regenerative aesthetics. While many brands are just beginning to explore this innovative ingredient, the true differentiator lies not just in having PN in a formula, but in its sourcing, purity, and the technological expertise behind its integration into stable and effective final products. Our strength in delivering a superior Polynucleotide Powder stems from a focused synergy between product-specific expertise and manufacturing excellence. By choosing our Polynucleotide Powder, you are not just selecting an ingredient; you are leveraging a partnership built on purity, scientific insight, and the flexibility to create a uniquely powerful end-product.

Polynucleotide (PN) Powder
Why our Polyglutamic Acid (PGA) powder?
1. Precision-Engineered Molecular Weight Profiles for Targeted Efficacy

We offer targeted MW profiles (e.g., 500-800 kDa for surface repair & intense hydration, or 1200-1500 kDa for deep dermal remodeling and collagen stimulation). Our high-purity batches consistently achieve over 98% polynucleotide content, with fragment length variability of less than ±5%, ensuring your formulations deliver reliable and reproducible biological results batch after batch.

2. Validated Bio-Activity & Enhanced Cellular Uptake

Purity is not just a percentage; it's about preserving the structural integrity of the DNA fragments for optimal bio-communication. Our gentle, low-temperature isolation method protects the nucleotide sequences, preventing denaturation.

3. OEM Advantage: From Ingredient Supplier to Co-Development Partner

This is where we transcend being a mere supplier. Our near-20 years of experience are at your disposal to create a truly unique product. Don't just buy a standard powder. We can co-develop a custom PN blend specifically for your product's target application—be it a serum for fine lines, a treatment for post-procedure recovery, or a scalp revitalization solution. This creates a unique, patentable selling point for your brand.

COA
Item Specification Result Test Method
Appearance White to off-white powder Conforms Visual
Odor Characteristic, odorless Conforms Organoleptic
Identification Positive Positive HPLC/UV
Assay (Polynucleotide Content) ≥99.0% 99.36% HPLC
pH (1% solution) 6.0–8.0 7.1 pH Meter
Molecular Weight (Average) 300–600 kDa 485 kDa GPC
Loss on Drying ≤5.0% 2.18% USP<731>
Ash Content ≤1.0% 0.42% USP<281>
Solubility Soluble in water Conforms Visual
Heavy Metals ≤10 ppm <10 ppm ICP-MS
Lead (Pb) ≤2.0 ppm <1.0 ppm ICP-MS
Arsenic (As) ≤1.0 ppm <0.5 ppm ICP-MS
Cadmium (Cd) ≤1.0 ppm <0.5 ppm ICP-MS
Mercury (Hg) ≤0.1 ppm <0.05 ppm ICP-MS
Total Plate Count ≤1,000 cfu/g 120 cfu/g USP<2021>
Yeast & Mold ≤100 cfu/g <10 cfu/g USP<2021>
E. coli Negative Negative USP<2022>
Salmonella Negative Negative USP<2022>
Staphylococcus aureus Negative Negative USP<2022>
Endotoxin ≤0.25 EU/mg 0.11 EU/mg LAL Test
Nucleotide Purity (A260/A280 ratio) 1.8–2.0 1.92 UV Spectrophotometer
Residue on Ignition ≤0.5% 0.21% USP<281>
Applications of Polynucleotide (PN) Powder
  • Widely used in anti-aging skincare formulations to promote skin regeneration, elasticity, and hydration.
  • Commonly applied in medical aesthetics and mesotherapy for improving skin texture, reducing wrinkles, and repairing photoaged skin.
  • Included in wound healing creams and serums to accelerate tissue recovery and cell proliferation.
  • Used in hair growth products to stimulate hair follicle activity and strengthen the scalp barrier.
  • Suitable for cosmetic injectables and dermal fillers as a biocompatible skin-repairing ingredient.
  • Added in premium facial masks and ampoules for deep rejuvenation and post-laser recovery.
  • Can be combined with ingredients like Hyaluronic Acid, Niacinamide, or Peptides for synergistic effects in skin repair and moisturization.
Recommended Dosage
  • Topical formulations: 0.05% – 0.5% depending on product type
  • Injectable solutions (cosmetic use): 0.1% – 2.0% (under professional supervision)
  • Serums and creams: 0.1% – 1.0%
  • Hair care products: 0.05% – 0.5%
PN Powder Supplier: Bulk, OEM, & Manufacturer

Ready to create a regenerative product that truly stands out? Let's talk partnership. We are your dedicated Polynucleotide (PN) Powder Supplier and Manufacturer, specializing in Bulk raw material and custom OEM formulations. We offer the market's highest verified-purity PN, a key advantage that ensures your finished products deliver superior cellular regeneration and visibly better results for your clients. We operate under multiple global certifications, giving you peace of mind on quality and compliance. Stop wasting time with general suppliers—connect directly with the manufacturer who can guarantee the efficacy of your key ingredient.

Frequently Asked Questions
QIs PN safe for skin?
Yes, PN is biocompatible and naturally derived, making it safe for sensitive skin and medical-grade cosmetics.
QWhat's the difference between PN and PDRN?
PN is a broader form of polynucleotides with a range of molecular weights, while PDRN is a specific type derived from salmon DNA. Both are used for skin regeneration.
QCan PN be combined with other active ingredients?
Yes. PN works well with moisturizing and collagen-boosting actives such as hyaluronic acid and peptides.
QDoes PN cause irritation?
PN has very low irritation potential and is suitable for post-procedure or sensitive-skin formulations.
QIs PN natural or synthetic?
PN is usually extracted from natural sources such as salmon DNA, purified, and refined for cosmetic or pharmaceutical use.
QWhat type of products include PN?
PN is found in high-end serums, anti-aging creams, injectable solutions, and post-laser repair products.

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