At the forefront of advanced skincare, Polynucleotide (PN) Powder, also known as DNA Sodium or DNA Cellular Repair Complex, is gaining recognition for its remarkable ability to rejuvenate and restore skin health. This powerful ingredient works by delivering fragments of DNA to the skin, which act as biological signals to stimulate your skin's own repair mechanisms. The result is a visible improvement in skin density, elasticity, and hydration, effectively reducing the appearance of fine lines and wrinkles for a more youthful and resilient complexion.
In the current market, PN-based products are creating a new niche in regenerative aesthetics. While many brands are just beginning to explore this innovative ingredient, the true differentiator lies not just in having PN in a formula, but in its sourcing, purity, and the technological expertise behind its integration into stable and effective final products. Our strength in delivering a superior Polynucleotide Powder stems from a focused synergy between product-specific expertise and manufacturing excellence. By choosing our Polynucleotide Powder, you are not just selecting an ingredient; you are leveraging a partnership built on purity, scientific insight, and the flexibility to create a uniquely powerful end-product.
We offer targeted MW profiles (e.g., 500-800 kDa for surface repair & intense hydration, or 1200-1500 kDa for deep dermal remodeling and collagen stimulation). Our high-purity batches consistently achieve over 98% polynucleotide content, with fragment length variability of less than ±5%, ensuring your formulations deliver reliable and reproducible biological results batch after batch.
Purity is not just a percentage; it's about preserving the structural integrity of the DNA fragments for optimal bio-communication. Our gentle, low-temperature isolation method protects the nucleotide sequences, preventing denaturation.
This is where we transcend being a mere supplier. Our near-20 years of experience are at your disposal to create a truly unique product. Don't just buy a standard powder. We can co-develop a custom PN blend specifically for your product's target application—be it a serum for fine lines, a treatment for post-procedure recovery, or a scalp revitalization solution. This creates a unique, patentable selling point for your brand.
| Item | Specification | Result | Test Method |
| Appearance | White to off-white powder | Conforms | Visual |
| Odor | Characteristic, odorless | Conforms | Organoleptic |
| Identification | Positive | Positive | HPLC/UV |
| Assay (Polynucleotide Content) | ≥99.0% | 99.36% | HPLC |
| pH (1% solution) | 6.0–8.0 | 7.1 | pH Meter |
| Molecular Weight (Average) | 300–600 kDa | 485 kDa | GPC |
| Loss on Drying | ≤5.0% | 2.18% | USP<731> |
| Ash Content | ≤1.0% | 0.42% | USP<281> |
| Solubility | Soluble in water | Conforms | Visual |
| Heavy Metals | ≤10 ppm | <10 ppm | ICP-MS |
| Lead (Pb) | ≤2.0 ppm | <1.0 ppm | ICP-MS |
| Arsenic (As) | ≤1.0 ppm | <0.5 ppm | ICP-MS |
| Cadmium (Cd) | ≤1.0 ppm | <0.5 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | <0.05 ppm | ICP-MS |
| Total Plate Count | ≤1,000 cfu/g | 120 cfu/g | USP<2021> |
| Yeast & Mold | ≤100 cfu/g | <10 cfu/g | USP<2021> |
| E. coli | Negative | Negative | USP<2022> |
| Salmonella | Negative | Negative | USP<2022> |
| Staphylococcus aureus | Negative | Negative | USP<2022> |
| Endotoxin | ≤0.25 EU/mg | 0.11 EU/mg | LAL Test |
| Nucleotide Purity (A260/A280 ratio) | 1.8–2.0 | 1.92 | UV Spectrophotometer |
| Residue on Ignition | ≤0.5% | 0.21% | USP<281> |
Ready to create a regenerative product that truly stands out? Let's talk partnership. We are your dedicated Polynucleotide (PN) Powder Supplier and Manufacturer, specializing in Bulk raw material and custom OEM formulations. We offer the market's highest verified-purity PN, a key advantage that ensures your finished products deliver superior cellular regeneration and visibly better results for your clients. We operate under multiple global certifications, giving you peace of mind on quality and compliance. Stop wasting time with general suppliers—connect directly with the manufacturer who can guarantee the efficacy of your key ingredient.