High-Quality Sophora Root Extract matrine powder Supplier, Manufacturer

CAS No.: 519-02-8

Specification: 10-98% Matrine

Appearance: Yellow brown to white fine powder

Test Method: HPLC

Solubility: Soluble in ethanol, slightly soluble in water

Applications: Cosmetics,Skin Care

Package: 1–25kg or customized

Sample: 10–50g Sample For free

Storage: Cool dry place away from direct sunlight

Certificates: ISO22000, Kosher, Halal, Organic(EU), USDA, FSSC22000, FAD, SGS, cGMP

Shelf life: 2 years, Available in bulk, Private Label/OEM&ODM

Product Description

Matrine Powder (derived from Sophora flavescens root extract) is a highly purified natural bioactive ingredient. Its key active component, matrine (C15H24N2O, CAS 519-02-8), is a potent alkaloid recognized for its antioxidant, anti-inflammatory, antimicrobial, and immunomodulatory properties. This standardized 98% matrine powder ensures consistent potency for pharmaceutical, nutraceutical, and cosmetic formulations.

With the rising global demand for plant-based remedies and organic skincare, this extract offers a versatile solution. Utilizing optimized assisted ethanol extraction, the yield is increased by 60% compared to traditional methods, maintaining high purity while optimizing production efficiency. Whether for bulk industrial use or specialized private label formulations, this ingredient meets rigorous compliance standards including HPLC verification.

Why Choose Our Sophora Flavescens Root Extract?

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High Purity & Consistency

98% matrine (HPLC-verified) with residual solvents ≤0.5%. A low batch-to-batch coefficient of variation ensures precise dosage in final products like capsules or injections.

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Advanced Extraction

Our assisted ethanol extraction technology achieves 60% higher yields than traditional boiling, reducing waste and energy consumption by 35%. Annual production capacity reaches 500 tons.

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OEM/ODM Capability

20 years of experience providing customizable dosage forms (10-98% concentrations) and synergistic premixes. All products come with ready-to-use COA, MSDS, and cGMP-compliant data.

Technical Specifications (COA)

Item Specification Result Test Method
Assay (Matrine) ≥98.00% 98.36% HPLC
Appearance White fine powder Conforms Visual
Particle Size 100% pass 80 mesh Conforms USP <786>
Loss on Drying ≤5.00% 2.18% USP <731>
Heavy Metals ≤10 ppm <5 ppm ICP-MS
Solvent Residue ≤5000 ppm (Ethanol) <200 ppm GC-MS
Total Plate Count ≤1000 CFU/g <100 CFU/g USP <61>

Applications in Skincare & Cosmetics

Anti-aging: Combats oxidative stress to improve skin elasticity and reduce fine lines.
Acne Control: Regulates sebum secretion and inhibits acne-causing bacteria.
Brightening: Promotes even skin tone by naturally reducing melanin production.
Sensitive Skin Care: Relieves irritation and redness for gentle daily use.
Scalp Care: Used in shampoos to relieve itching and reduce dandruff.

Recommended Dosage Guidelines

Topical formulations (creams/lotions/serums): 0.1% - 2.0%

Shampoos/scalp products: 0.5% - 1.5%

Masks or ampoules: Maximum 3% for rinse-off products.

Note: Patch testing and stability testing are essential for final product formulation.

Frequently Asked Questions

1. Is matrine powder natural and safe for skin?

Yes. Matrine is a natural alkaloid extracted from the root of Sophora flavescens. It has a long history in traditional herbal medicine and is considered cosmetically safe within recommended dosage ranges.

2. How does Matrine help improve acne-prone skin?

Matrine regulates sebaceous gland activity, reduces the proliferation of Propionibacterium acnes, and relieves skin inflammation, making it an effective ingredient for anti-acne formulations.

3. What is the difference between Matrine and Oxymatrine?

Both are alkaloids from the Sophora plant. While Oxymatrine is often studied for pigment reduction, Matrine is more widely used for its superior anti-inflammatory and anti-aging properties in topical applications.

4. What is the shelf life of your Matrine Powder?

When stored in a cool, dry place away from direct sunlight and moisture, the standard shelf life is 24 months. We provide airtight packaging to ensure stability.

5. Can this powder be used in water-based serums?

High-purity matrine powder has good stability. While it is an alkaloid, it can be formulated into various delivery systems; however, pH adjustment and solubility testing in the specific vehicle are recommended.

6. Do you provide documentation for international compliance?

Yes, we provide comprehensive documentation including Certificate of Analysis (COA), Material Safety Data Sheets (MSDS), and technical data sheets to support your regulatory filings.

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