Explore our certified plant-based extracts and active nutritional compounds raw materials engineered for maximum bioavailability.
Analyzing market growth, consumer demographics, purity standards, and global supply chains.
Traditional B12 synthesis often relies on animal-derived pathways or toxic chemical refining. Our ODM Vegan B12 utilizes non-GMO microbial fermentation strains (such as Pseudomonas denitrificans) to deliver a 100% clean-label, bio-equivalent active compound matching plant-based standards.
Meeting the complex criteria of international health authorities requires rigorous proof. Our manufacturing lines carry complete compliance documentation, including Kosher, Halal, USDA Organic, and Vegan Society approvals to simplify your border entry protocols.
From Cyanocobalamin to natural, highly active forms like Methylcobalamin, Adenosylcobalamin, and Hydroxocobalamin, we offer customized micro-encapsulated spray-dried powders and liquid formulations to fit distinct application delivery methods.
B2B procurement agents from North America, the European Union, and the Asia-Pacific region are increasingly demanding full transparency in raw material supply chains. Vitamin B12, or cobalamin, is fundamentally synthesized only by specific bacteria and archaea. Traditional extraction methods relied heavily on animal organ processing, which is completely unusable for modern clean-label and vegan consumers. As an industry-leading ODM partner, we leverage precision fermentation bioreactors to synthesize cobalamin in an animal-free system, validating every batch with HPLC (High-Performance Liquid Chromatography) testing to guarantee active molecule counts and exceptional stability.
Building sustainable, scalable, and biological solutions for nutritional deficiencies worldwide.
Modern functional foods and dietary supplements require ingredients that can withstand harsh industrial manufacturing conditions. Our macro-level solutions target stability, compatibility, and biological potency. By integrating deep biotechnology research with global raw-material logistics, we assist brands in developing functional beverage formulas, chewable tablets, sublingual drops, and fortified vegan meat alternatives.
Whether you require bulk raw powders, premium granular structures, or tailored liquid premixes, our team handles the complex bioprocessing steps so you can focus on brand equity and market launch strategies. We maintain continuous supply stability through strategic depots in global logistics hubs.
A Global Leader in Natural Ingredients
Benefiting from the solid foundation provided by its parent company, Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc. focuses on researching, developing, producing and selling healthy natural ingredients. With more than two decades of industry experience, it has become a leader in the field, specializing in providing high-quality plant extracts and customized solutions to global customers.
Services meet the needs of industries including herbal medicine, health foods, dietary supplements, food and beverages, daily chemicals and cosmetics.
Our operations are supported by three companies — Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc., and Shaanxi Tianben Kangyuan Biotechnology Co., Ltd. — which together operate 3 production bases covering more than 100 acres and process more than 3,000 tons of plant raw materials each year. The product range includes more than 200 plant extracts, and we also provide a variety of certified organic products to meet the global demand for environmentally friendly and healthy solutions. Exporting to 60% of the world's countries, serving more than 200 countries and regions and more than 500 customers from all walks of life.
Deep scientific analysis of genetic optimization, biosynthesis pathways, and stability preservation.
Our team utilizes metabolic engineering strategies to modify microbial strains, upgrading their intrinsic biosynthetic rates. Through optimization of key enzymic checkpoints in the cobalamin pathway (specifically the aerobic or anaerobic branch of uroporphyrinogen III transformation), we have successfully increased yield density by 40% over standard wild strains.
Due to the sensitivity of Vitamin B12 to light, heat, and moisture, our R&D center has developed a lipid-based microencapsulation process. The active molecules are enclosed within a plant-derived lipid shell, ensuring zero nutrient loss under acidic stomach environments and releasing the active compound effectively within the small intestine for optimal absorption.
As consumer preferences align with bio-active nutrition, our manufacturing facility is constantly adapting. Our technical roadmap highlights ongoing work with co-enzyme blends to provide stable compounds for high-end pharmaceutical applications. We are also pursuing carbon-neutral fermentation cycles by utilizing side-stream agricultural byproducts as growth media for our microbial bioreactors, effectively lowering environmental impact indices for our global ODM brand partners.
Our first factory was established in 2012 in Sanyuan City, Xi'an, four years after our company was founded. At that time, our production experience was still in its early stages, and we faced many challenges as we worked to refine our processes. However, we remained committed to continuous improvement, investing heavily in technology, training, and quality control to strengthen our capabilities. These early efforts laid a strong foundation for our future growth, shaping the high standards of excellence that we uphold today.
Powder collection, crushing and sieving, mixing and drying processes are all performed in a Class 100,000 cleanroom environment. Our operators strictly follow hygiene protocols and wear sterile gowns, masks and gloves to maintain product purity and safety, thus ensuring that we provide our customers with high quality standards and reliable ingredients.
Ensuring effortless custom clearance, seamless cross-border technical declarations, and third-party validation.
Our regulatory affairs division provides active support with US FDA DMF (Drug Master File) submissions, structure-function claim validations, and GRAS (Generally Recognized as Safe) notifications to fast-track your retail commercialization.
Navigating Europe's complex EFSA Novel Food regulations can be challenging. We prepare comprehensive dossiers detailing toxicological reports, heavy metal profiles, and metabolic assays to ensure frictionless EU customs clearances.
Backed by our global network of storage hubs, we provide customized clearance solutions for key logistics centers in the EU, USA, and South America, maintaining a fully temperature-controlled, end-to-end shipping process.
For global dietary supplement operations, quality control consistency is paramount. Botanical Cube Inc. ensures that every single batch of ODM Vegan Vitamin B12 undergoes comprehensive purity validation. Our modern analytics laboratories are equipped with Ultra-Performance Liquid Chromatography (UPLC), Gas Chromatography-Mass Spectrometry (GC-MS), and Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to monitor potential trace contaminants. We provide a complete Certificate of Analysis (COA) containing assay metrics, moisture levels, microbiological limits, heavy metals content (Lead, Arsenic, Cadmium, Mercury), and pesticide clearance. This exhaustive validation minimizes regulatory risks, allowing B2B buyers to confidently scale their brands across competitive global markets.
Essential technical and regulatory insights for professional B2B buyers and product formulators.
A1: Our vegan Vitamin B12 is produced using modern microbial fermentation technology. We culture specialized, non-GMO bacterial strains (specifically *Pseudomonas denitrificans*) in a plant-based broth medium. After fermentation, the biomass undergoes separation, purification, and crystallization in our Class 100,000 cleanroom, yielding highly pure, animal-free cobalamin.
A2: We offer four primary forms of cobalamin tailored to your product needs: Cyanocobalamin (stable and cost-effective), Methylcobalamin (naturally active coenzyme form), Adenosylcobalamin (mitochondrial-active form), and Hydroxocobalamin (highly stable therapeutic form). We provide these as fine powders, granular formats for tableting, or liquid premixes.
A3: Quality assurance is managed through the integrated operations of Xi'an Tianben Bioengineering Co., Ltd. and Botanical Cube Inc. Our facilities operate under strict GMP guidelines, and all processing is handled within a certified Class 100,000 cleanroom. Every batch is validated through HPLC testing and accompanied by a detailed Certificate of Analysis (COA) detailing active assay levels, heavy metal limits, and microbiological purity.
A4: Our products are supported by a full suite of international certifications, including ISO 22000, Kosher, Halal, USDA Organic, and Vegan Society approvals. We also assist partners with regulatory dossier preparation, including stability study documentation and heavy metal statements for US FDA and EU EFSA clearances.
A5: Our standard MOQ for stock powders starts at 25kg, while custom formulations, special granulations, or microencapsulation orders typically require a 100kg minimum. Depending on the customization complexity, standard shipping lead times range from 7 to 15 business days from our factory.
Expand your dietary supplement lines with our premium active compounds, manufactured under strict international quality standards.
Botanical
