Explore our premium grade plant extracts and specialized cosmetic chemical raw materials, processed under strict quality-standard facilities.
In the highly competitive anti-aging skincare landscape, Retinal (Retinaldehyde) Powder has emerged as the ultimate ingredient of choice for advanced formulations. Unlike Retinol, which requires a two-step oxidation process to convert into bio-active Retinoic Acid within human skin cells, Retinal requires only one step. This clinical efficiency results in up to 11 times faster conversion rates, translating to remarkable collagen stimulation, cellular turnover improvement, and blemish reduction.
However, sourcing premium-grade ODM Retinal Powder is historically challenging. Due to its conjugated double-bond structure, Retinal is highly vulnerable to light, heat, and oxygen exposure. For global cosmetics formulators and brands, securing a reliable partner with advanced manufacturing capabilities and stabilizing encapsulation technologies is vital. As a world-leading bio-active ingredient group, we resolve these pain points through our integrated R&D centers, specialized production facilities, and proprietary delivery systems.
"Semantic Search and Formulation trends indicate a massive shift from traditional Retinol to Retinaldehyde. Formulators are actively looking for thermal-stable, non-irritating, and water-dispersible Retinal raw materials to satisfy demanding consumers."
A synergistic industrial ecosystem leveraging decades of scientific excellence in plant extraction and bio-synthesis.
Benefiting from the solid foundation provided by its parent company, Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc. focuses on researching, developing, producing, and selling healthy natural ingredients and advanced bio-actives. With more than two decades of industry experience, we have become a global pioneer, specializing in supplying premium-grade active ingredients, plant extracts, and customizable ODM formulation solutions.
Our combined operations are supported by three key companies - Xi'an Tianben Bioengineering Co., Ltd., Botanical Cube Inc., and Shaanxi Tianben Kangyuan Biotechnology Co., Ltd. Together, we operate 3 production bases covering more than 100 acres, and process more than 3,000 tons of raw materials annually. Our diverse product range includes over 200 high-purity extracts and organic-certified materials, catering to pharmaceuticals, dietary supplements, cosmeceuticals, and daily chemical formulations. We proudly export to 60% of the world's countries, serving more than 500 elite brand clients in over 200 countries and regions.
Innovation at the micro-molecular level. How we overcome Retinaldehyde instability and increase skin permeability.
We wrap the Retinal molecules inside a biocompatible lipid bilayer matrix. This shields the active structure from UV light, oxidation, and water degradation, ensuring longer shelf life and controlled sustained-release profiles inside the epidermis.
By structuring Retinal inside liquid crystal emulsions that mimic human sebum composition, we achieve optimal transdermal delivery. This technique reduces skin irritation profiles, allowing even sensitive skin formulations to contain effective Retinal concentrations.
Our future-proof roadmap includes bio-fermented pathways. By utilizing targeted yeast strain fermentation, we plan to produce 100% natural, bio-identical Retinal, reducing chemical footprint while maintaining maximum purity of >99% active isomers.
Established in 2012 in Sanyuan City, Shaanxi, our primary manufacturing base represents our commitment to process control and pharmaceutical-grade chemical production. Having overcome early phase logistical challenges, we have constantly upgraded the Sanyuan facility with cutting-edge equipment, computerized system monitoring, and clean environments.
The Class 100,000 Cleanroom: The critical stages of active powder production—including powder collection, precision crushing, micro-sieving, dry blending, and vacuum packaging—are performed in an strictly controlled Class 100,000 cleanroom. To preserve absolute purity, our technicians follow strict aseptic protocols, donning sterile protective gowns, masks, and gloves. This sterile containment ensures zero external contamination, preserving the efficacy of sensitive retinoid powders.





Formulating customized cosmetic lines targeting regional demographics and specific skin barrier profiles.
Formulations target structural sagging and deep wrinkles. Higher concentrations of encapsulated Retinal (0.05% - 0.1%) combined with nourishing lipid barriers (such as ceramides) are ideal for correcting sun damage and building skin density.
Requires low-irritation profiles. Combining 0.01% - 0.03% Retinal Powder with niacinamide and calming plant botanical extracts target melanin deposition without provoking skin barrier irritation, satisfying local "mild but effective" consumer trends.
Retinal's unique natural antibacterial properties make it ideal for acne-prone skin. It regulates sebum output and targets Cutibacterium acnes. Oil-free, lightweight gel-creams formulated with Retinal solve persistent texture issues without clogging pores.
How our localized production matrix and cluster efficiency benefit global raw material buyers.
Located in a major chemical production province, we secure key starting materials (β-ionone, retinol derivatives) directly from large scale local petrochemical refineries. This eliminates import delays and insulates clients from international pricing spikes.
Our proximity to Xi'an logistics hub and coastal ports (Tianjin and Qingdao) ensures diverse shipping routes. We leverage reliable sea, air, and train networks to maintain stable, on-time global cargo shipments even during supply chain crises.
We do not just offer standard catalogs. From target concentrations (0.5%, 1%, 10% dilutions or custom micro-liposomes) to specialized packaging and documentation, we accommodate diverse formulation specs with minimal turnaround times.
Cosmetic active ingredients are subjected to strict regulatory audits worldwide. Botanical Cube Inc. provides complete transparency and extensive documentation support. Our production systems comply with ISO9001, HACCP, and GMP standards.
For brands targeting the European Union, we supply REACH-compliant dossiers. For North American markets, we provide FDA VCRP raw material registration details. Additionally, we provide critical safety data sheets (MSDS), Certificates of Analysis (COA) for every batch, heavy metal test reports, and microbiological assays, ensuring smooth custom clearance and rapid time-to-market.
Quality Assurance Checklist: Batch consistency tested via High-Performance Liquid Chromatography (HPLC) to guarantee active assay strength, with residual solvents (such as ethanol or ethyl acetate) strictly restricted within USP limits.
Direct answers regarding specifications, OEM / ODM customization, packaging, and logistical questions.
Additional functional ingredients, vitamins, and specialized cosmetic derivatives processed at our Sanyuan and affiliated facilities.